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Eric Siemers on Aducanumab Approved to Treat Alzheimer’s Disease

COMMENT A historic moment was achieved with the accelerated approval by FDA of aducanumab for the treatment of Alzheimer’s disease. This decision will not be made in the absence of controversy, given the results from two identically designed pivotal trials for ...

Eric Siemers on Biogen/Eisai Halt Phase 3 Aducanumab Trials

COMMENT Alzheimer’s patients and their families suffered yet another blow when Biogen announced that the EMERGE and ENGAGE Phase 3 trials of aducanumab were being stopped for futility. A more complete understanding of the potential causes of yet another negative ...

Eric Siemers on A Blood Test for AD?

COMMENT Wyss-Coray et al. report an investigational diagnostic test for AD that could represent a major advance for the field if their results can be replicated. A method of improving the diagnostic accuracy of AD would be valuable immediately to ensure that ...

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