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Stefano Sensi on Results from Verubecestat APECS Trial Published

COMMENT I side with the closing comments of David Knopman: "To be blunt, Aβ lowering seems to be an ineffective approach, and it is time to focus on other targets to move therapeutics for Alzheimer’s disease forward." We do need a fresh start and also ...

Stefano Sensi on Biogen/Eisai Halt Phase 3 Aducanumab Trials

COMMENT The failure of the Phase 3 aducanumab trial is another warning that the field must take a different approach. Some authors have already called for a rejection of the amyloid hypothesis, new and old players like tau-related pathology microglia activation ...

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