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Boris Schmidt on Dyeing Worms for an Extra-Long, Healthy Lifespan?

COMMENT The remarkable life-extending activity of the high curcumin concentrations requires additional experimental data for evaluation. Aqueous solutions of curcumin are not stable over three days (see decreased toxicity in zebrafish embryo); there are even ...

Boris Schmidt on Presenilin Loss of Function—Plan B for AD?

COMMENT Shen and Kelleher's PNAS paper raises interesting questions, and it compiles data in favor of provocative answers. But what incontrovertible data did the authors ignore? I agree with the comments made by Christian Czech. The pharmacology of γ ...

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