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Wiep Scheper on Aβ Assault on Neurons Targets ER, Calcium

COMMENT Our lab previously reported activation of the UPR in AD neurons (Hoozemans et al., 2005). In the current paper, Ferreiro et al. show induction of BiP levels, as well as decreased pro-caspase-12 levels induced by Aβ1-40. This may indicate that the ER ...

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