6 RESULTS
COMMENT I was disappointed but also not completely surprised. Reasons include the small sample, the late increase in dose, and the unknown test characteristics of the four cognitive tests in this population, especially since some of the participants did not have ...
COMMENT I think that anything that is unproven/not investigated for Alzheimer’s disease should not be used! I never prescribe supplements, but do advise that people follow a healthy lifestyle, including meals that contain all the necessary vitamins. If ...
COMMENT It is very difficult to make comments based on the press release only. Having said that, I was never optimistic about this drug. It has a different isoform as all the others (Ig4 vs Ig1); has little ARIA, which, in my opinion, also indicates less efficacy ...
COMMENT IDEAS is a much-needed study. The main outcome from the perspective of third payers will be health economics. It is likely that with the current pricing of amyloid PET scans and the absence of any specific, approved, anti-amyloid-directed therapy, the ...
COMMENT I applaud the EMA for taking this, and the previous, initiative, since they clearly may boost industry to use these markers in future clinical trials. Further, both EMA guidelines clearly underline the rationale of the concept reflected in the Dubois set ...
COMMENT Age and Atrophy: Nothing to Worry About? In this paper, Burgmans et al. argue that previous studies suggesting that age causes cortical atrophy on MRI may be flawed because they included subjects who, in fact, had preclinical dementia. If true, this would ...
