4 RESULTS
COMMENT I am impressed with the donanemab data for several reasons. The design is informed based on previous studies. The titration up is appropriate. The selection of intermediate tau load is novel. The pyro-glu epitope is downstream from oligomeric species, ...
COMMENT This research by Donner and colleagues makes important contributions in understanding mechanistically how amyloid is deposited in cerebral amyloid angiopathy. It appears that platelets play an important role in Aβ fibrillization. Specifically, amyloid ...
COMMENT The data from the bapineuzumab trial presented at EFNS has been highly informative, if not disappointing. It reinforces, conceptually, that amyloid and cognition are not related. This has been debated for over 40 years, dating back to Blessed, Tomlinson, ...
COMMENT This study by Willis et al. is highly informative about demographics and life expectancy in Parkinson's disease. The main findings are that life expectancy is shorter than might have been reported before, and that dementia is very common and is a ...
