Miguel Rodríguez-Manotas on Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.
COMMENT This paper opens a new way to fight AD. It breaks the paradigm in the sense that upregulating, but not inhibiting, presenilin leads to decreased Aβ42 levels. mmanotas 0 ...