Hanno Roder on Treatment of Alzheimer's disease with anti-homocysteic acid antibody in 3xTg-AD male mice.
COMMENT One does not have to go so far as to postulate a different pathology in mice vs. humans to understand the discrepancy. The Aβ-induced cognitive defects in mice could become apparent because of the tremendous overexpression in mice. In humans, Aβ probably ...