3 RESULTS
COMMENT Here the authors did a systematic analysis of Toll-like receptor (TLR) gene expression in the brains of AD patients versus controls and they found a significant increase in specific members of this family, including TLR2, 4, and 5. To explore the role of ...
COMMENT In this study, the authors have found that TGF-β signaling inhibits the natural properties of macrophages to clear Aβ and infiltrate the CNS of APP mice. Knocking out such signaling events was found to improve both the brain infiltration of bone marrow ...
COMMENT I would like to thank Erene Mina and Drs. Walker and Jucker. They provide insightful comments regarding specific aspects of the study. I'd like to address a few points here. The first one regards irradiation and its effects on the blood-brain barrier ...
