3 RESULTS
COMMENT I think the donanemab data are interesting and possibly encouraging. The key features are: Donanemab lowers amyloid promptly and significantly to essentially normal levels; Once normalized, the sponsor stopped dosing; The incidence of ARIA was significant ...
COMMENT This is an interesting study, as are most studies on centenarians. I suspect that these survivors have some unique genetic resilience factors operating. Lifestyle might be part of it, but I am more inclined to invoke a “polygenic resilience” in these ...
COMMENT This is an interesting approach to the assessment of early diagnostic tests for AD. As for the MCI aspect of the study, I think it is a nice demonstration of deficits in spatial memory in amnestic MCI, which certainly would be consistent with the ...
