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Ruth Perez on Novel Cell-Based Parkinson's Model Shows Promise

COMMENT The work by Tim Greenamyre, Todd Sherer, and colleagues provides a novel cellular model of chronic environmental toxin exposure that may well be relevant to Parkinson’s disease (PD). Although the authors did not use dopaminergic neurons (which they ...

Ruth Perez on Dopamine Renders α-Synuclein Toxic to Neurons

COMMENT I appreciated reading the above discussion of Xu et al.’s paper regarding a potential role for α-synuclein, 14-3-3, and dopamine in the pathogenesis of Parkinson's disease. I agree that α-synuclein and dopamine are a toxic mix. I do, however, want to ...

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