3 RESULTS
COMMENT This is a thoughtful summary of the numerous reports and findings over the last decade on TDP-43 pathology restricted to the limbic system common in elderly patients and often associated with hippocampal sclerosis and/or Alzheimer’s disease. While this ...
COMMENT These are certainly interesting novel mouse models for future studies on ALS/FTD pathogenesis. Several aspects seen in these novel mouse models confirm previous findings in comparable transgenic mouse and rat models, namely that overexpression of UBQLN2 ...
COMMENT The paper clearly demonstrates that arginine methylation of FUS is an important modulator for nuclear import of FUS and its homologues, TAF15 and EWS, as demonstrated in vitro and in cell culture. In my opinion, the most exciting finding is the difference ...
