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Michael Myre on Cell Cycle and AD

COMMENT As described above, the cell-cycle phenotype detected in both human and transgenic mouse AD models is an observation that deserves far more attention than it currently receives. Although many aberrant neuronal conditions are detected pathologically in AD ...

Michael Myre on AICD—Salute to Salutary Effects

COMMENT I wonder why there is no mention of the neuropathology, including neuritic plaques and neurofibrillary tangles, that develops in most, but not all (see Argellati et al., 2006) individuals afflicted with Down syndrome. BACE1 and BACE2 levels have been ...

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