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Elliott Mufson on Caspase activation precedes and leads to tangles.

COMMENT The findings of Alix de Calignon and colleagues are interesting and support several studies using human AD tissue that show caspase plays a pivotal role in tangle formation. However, given the recent indications that AD has a preclinical phase of between ...

Elliott Mufson on Looking outside the Brain for Early Signs of AD

COMMENT The search for a biomarker that distinguishes AD from other neurological dementias is a fertile research area for both clinical, basic, and biotech investigators. In this article, findings are presented demonstrating the ability of gene array technology ...

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