3 RESULTS
COMMENT Quiroz and colleagues provide the first report of AV1451 tau-PET in a cohort of at risk for autosomal-dominant Alzheimer's disease (ADAD) related to the PSEN1 E280A mutation. By studying mutation carriers at various stages of the disease cascade ...
COMMENT The report provides an interesting approach using a heterozygous-dominant disease, and provides some clear translatability to many ADAD mutations. However, the mutation that was the focus of this research was a deletion, and most ADAD-causing mutations ...
COMMENT The association of seizures and epilepsy with Alzheimer’s disease (AD) is well established. However, there is increasing recognition that seizures may occur in milder stages of the disease (Vossel et al., 2016; Zarea et al., 2016), and that this may be a ...
