4 RESULTS
COMMENT The evidence to date is that there may be a very small risk of transmission of pathogenic Aβ in the course of neurosurgical procedures, and that over several decades this can lead to the development of cerebral amyloid angiopathy. Neurosurgery carries ...
COMMENT The data from the SPRINT MIND study are very encouraging, but the interpretation may not be quite as straightforward as suggested. It is certainly possible that the benefits in terms of cognition and MRI changes resulted directly from the aggressive ...
COMMENT Caution is warranted in interpreting the association between midlife hypertension and AD. Hypertension tends to exacerbate atherosclerosis and small vessel disease, and so increase the risk of vascular dementia. It may also lead to impaired clearance of ...
COMMENT I understand that further animal toxicity studies are in progress. However, over 100 patients have received intracerebral GDNF infusion by one route or another with no clinical toxicity and I can't believe that GDNF treatment won't be available ...
