Dezhi Liao on Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation.

COMMENT The abnormal acetylation of tau lysine 280 (K280) has recently received great attention in AD research. It has been proposed to be a novel pathological signature of AD (see Cohen et al., 2011). The present paper has characterized the effect of deleting ...

Dezhi Liao on Tau’s Synaptic Hats: Regulating Activity, Disrupting Communication

COMMENT The paper from Lennart Mucke’s group demonstrates that Aβ-induced synaptic dysfunction depends upon cellular alterations in tau proteins. In contrast, our paper (Hoover et al., 2010) mainly focuses on how cellular alterations in tau proteins themselves ...

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Dezhi Liao on Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation.

Dezhi Liao on Tau’s Synaptic Hats: Regulating Activity, Disrupting Communication

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