Virginia Lee on α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
COMMENT Our experience working with α-synuclein is similar to Lashuel and colleagues’ in that we always recover α-synuclein as monomers. We have never observed tetramers using similar biochemical and biophysical techniques in the analyses of recombinant α ...