Michael K. Lee on α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
COMMENT The report from the collaborative Lashuel group is a careful but partial rebuttal of two recent reports (Bartels et al., 2011 and Wang et al., 2011) that concluded that α-synuclein in cells exists as a stable tetramer. In the current report, Fauvet et al. ...