3 RESULTS
COMMENT In my opinion, this is the clearest indication that Alzheimer's disease is not a single entity, despite the ubiquity of amyloid plaques, and should not be treated as one. Therapies that seek to slow progression of dementia are unlikely to be ...
COMMENT This is a beautiful paper showing plaque growth in vivo. I cordially disagree on one point: the authors state that the speed of an individual plaque's growth is surprising because of prior in vitro studies of protein aggregation showing a slow, time ...
COMMENT This is a beautiful paper that follows a large body of excellent work from these investigators. However, no data is presented as to how the disruption of the interaction between SAP and amyloid fibrils by their drug candidate affects the fate of the ...
