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William Klein on Oligomers in AD: Too Much of a Bad Thing?

COMMENT Response to comment by Vincent Marchesi Dr. Marchesi provides a thoughtful summary of our study and calls attention to an issue that's of central concern to us—specificity. AD is so memory-specific, especially early on, that one would hope to ...

William Klein on Normal Prion Protein Signals with Fyn

COMMENT Coupling of cellular prion proteins to Fyn is a real surprise, but maybe it shouldn't be. Fyn keeps popping up. Shirazi and Wood showed that tangle-bearing neurons in AD have a hefty overload of Fyn. Gloria Lee showed Fyn and tau co-localize. Gail ...

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