9 RESULTS
COMMENT This study complements recent and past work showing that genetic background can significantly influence the onset, extent, and progression of amyloid-associated pathology in mouse models. To the best of my knowledge, this line of investigation started in ...
COMMENT The Merck announcement is especially disappointing because the drug looked so promising when it was first described. Although clinical studies have made a lot of progress toward understanding the early phases of AD, I think the field is still struggling ...
COMMENT We are grateful to Drs. Westmark, Malinow, and Tanila for their positive comments on our study. We also appreciate the thoughtful letter from Drs. Mucke, Palop, Sanchez, and Johnson, and want to respond specifically to their comments, as they raise ...
COMMENT This study demonstrates experimentally what many years of research have taken for granted—that some of the basic tenets of adult neurogenesis observed in rodents also hold true in the primate brain. The Gould group has contributed much of what we know ...
COMMENT The new study by Thomas et al. provides surprising data that even acute bouts of psychosocial stress can have dramatic, long-lasting effects on hippocampal neurogenesis. Using a social dominance paradigm in which young adult male intruders are briefly ...
COMMENT This uses a clever experimental design to ask whether newborn hippocampal neurons are activated by learning and memory, and if so, how their involvement compares to that of older, established granule cells. The authors find that newborn hippocampal ...
COMMENT The new study by Meshi et al. convincingly demonstrates that hippocampal neurogenesis is not required for behavior improvements following environmental enrichment. The experimental design is exceptionally clean, and the work is beautifully done. In fact, ...
COMMENT The paper by Ziv et al. brings together two often disparate fields of study: immunology and neuroscience. The group of Michal Schwartz is one of a relatively few in the world who draws on tools of both trades to study how the immune and nervous systems ...
COMMENT The main point of commonality between our work on environmental enrichment and plaque deposition (Jankowsky et al., 2003) and that of Lazarov et al. is the demonstration that environment can substantially influence the level of amyloid and Aβ peptide in ...
