3 RESULTS
COMMENT These are two interesting studies shedding new light on APOE4 and its role on Aβ production/clearance by different CNS cell types and neuronal tau pathology. I was particularly intrigued by the finding in Wang et al. that not reduction of Aβ but the small ...
COMMENT Rhinn and colleagues report in this very interesting paper similar differential gene regulation in disease-free APOE4 carriers and non-APOE4 late onset Alzheimer’s disease (AD) patients, using differential co-expression analysis. The overlap in gene ...
COMMENT This is nice work by Hoover and colleagues providing yet another piece of important evidence for the role(s) of tau in the post-synapse. While we showed before that endogenous mouse tau is associated with the post-synaptic density (PSD) (Ittner et al., ...
