Alberto Serrano-Pozo, Bradley Hyman on Does Astrocyte Tau Cause Dementia?
COMMENT In this important study, Richetin et al. demonstrate that astrocytes in the hilus of the hippocampus dentate gyrus accumulate misfolded 3R-tau in Alzheimer’s disease (AD). Using an elegant lentiviral gene transfer approach in vivo (wild-type mice) and in ...