Eran Hornstein on TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes.
COMMENT This work of Yukio Kawahara and Ai Mieda-Sato is very interesting. It complements previous work from the groups of Don Cleveland, Bob Brown, and many others linking RNA metabolism to the pathology of TDP-43 in FTD and ALS. It also provides a strong clue ...