5 RESULTS
COMMENT Mitochondria and Alzheimer’s Disease: A Complex Interrelationship Recently, Coskun and colleagues (2004) reported that brains from patients with Alzheimer's disease (AD) present somatic mtDNA control-region mutations, especially in individuals older ...
COMMENT Embalming Amyloid-β: The Role for Aldehyde Stress in Alzheimer's Disease Zhang and colleagues present novel findings demonstrating that cholesterol derivative-aldehydes resulting from ozonolysis can accelerate the aggregation of Aβ into fibers. This ...
COMMENT Parkin and Mitochondria: Are They Allies in the War Against Parkinson’s Disease? This exciting study by Palacino and colleagues shows an alliance between two of the best-studied features of Parkinson's disease, namely, mitochondrial dysfunction and ...
COMMENT Is Redox Regulation of Development in Caenorhabditis elegans a Critical Issue? Shibata and colleagues (2003) present compelling evidence of reactive oxygen species (ROS) and oxidation of lipoprotein as important mediators of signal transduction. They ...
COMMENT Ceramide, Cholesterol, and Oxidative Stress In a very exciting study, Cutler and colleagues provide insight to link membrane-associated oxidative stress and neuronal degeneration in aging and Alzheimer disease (AD). Many lines of evidence suggest that ...
