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Brian Gordon on Plasma NfL Goes the Distance in Alzheimer’s

COMMENT Before we can say what utility NfL may have, we need to understand how levels of NfL discriminate between diseases states in a cross-sectional, one-off manner, as well as how it behaves over time. Understanding such a longitudinal change is critical for ...

Brian Gordon on Improving Tau PET: In Search of Sharper Signals

COMMENT In general, I think tau imaging data is very promising, but there is a lot we have to learn. Increased Aβ pathology can occur decades before the onset of dementia, while elevations in tau pathology are thought to occur nearer to the onset of cognitive ...

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