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Charles Glabe on Microglia Build Plaques to Protect the Brain

COMMENT This paper by Huang et al. reports a number of interesting observations that provide significant insights into the role of microglia in Alzheimer’s disease and into the mechanism of plaque biogenesis that have a number of implications for the amyloid ...

Charles Glabe on Enhancing Aβ Fibrillization Boosts Mouse Memory

COMMENT Alzheimer scientists have long known that amyloid plaques are not always associated with cognitive dysfunction. Indeed, some cognitively normal individuals have impressive numbers of insoluble amyloid plaques. Recent studies have shifted the focus to ...

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