Richard C. Mohs, Michela Gallagher on What Lies Beneath: Intracranial Probes Pick Up Hippocampal Seizures in AD

COMMENT This paper provides additional support for the growing body of data indicating that neuronal overactivity in the medial temporal regions of the brain are an integral part of the pathophysiology of early Alzheimer’s disease and probably play a role in ...

Michela Gallagher on Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model.

COMMENT This report by Sanchez et al. demonstrating improvements in molecular markers, synaptic function, and memory performance in hAPP mice points to overactivity as a therapeutic target. These data from a preclinical model of AD also match recent results from ...

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Richard C. Mohs, Michela Gallagher on What Lies Beneath: Intracranial Probes Pick Up Hippocampal Seizures in AD

Michela Gallagher on Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model.

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