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COMMENT This paper is a significant achievement. Along with recent datasets from the Allen Brain Institute and MIT, it represents the latest generation of Alzheimer's nuc-Seq atlases notable for the large number of samples and cells analyzed. The insights em
COMMENT These look useful and I wouldn’t be surprised if many groups took advantage. The current state of the art for this type of approach is an analogous pair of Cx3cr1-driven mice, which have the drawback, as the authors indicate, of also labeling other non-mi
COMMENT Thank you for this well-written article. I would like to add this recent study, which showed that nucleic acid binding activity is required for TDP-43-mediated toxicity in flies. C-terminal fragments of TDP-43 lack such activity, but are still capable of
