7 RESULTS
COMMENT The authors should publish the full study as soon as possible. The observed effect size is relatively small, and is only slightly greater than the minimal clinically important difference of ADAS Cog. So, I don't view this as a breakthrough. If they ...
COMMENT Definitely we need more randomize controlled trial evidence to back up any claims that any supplements / nutraceuticals / medical foods may improve cognitive symptoms in dementia or delay cognitive decline among individuals with normal cognition or mild ...
COMMENT A newly published paper by Yi Zeng and colleagues reported increasing cognitive impairment among oldest-old in China based on data from the Chinese Longitudinal Healthy Longevity Study (CLHLS) 1998 and 2008 surveys. The findings are relevant to the ...
COMMENT It would be interesting to study bilingual and monolingual elderly who have normal cognitive function, elevated risk of future dementia, subjective cognitive decline, or mild cognitive impairment, so we will have a complete picture of how bilingualism ...
COMMENT This is an exciting and timely project that will benefit scientific research and clinical practice in the long run. One difficulty I can foresee is that dementia is a long, pathological process rather than an event. So it would be very hard to define a ...
COMMENT This is very interesting. I am wondering how to relate those findings to the roles of folate in brain function and cognitive aging in humans. Folate provides one carbon group to methylate DNA and other substrates. In population-based studies, low folate ...
COMMENT I agree with Smith on the potential of B vitamins in preventing AD among a subgroup of persons with elevated homocysteine and/or suboptimal B vitamin status. I think personalized prevention is the way to go. pcmfl 0 ...
