3 RESULTS
COMMENT In this paper, the authors provide a comprehensive characterization of human prefrontal cortex tissue from 12 Alzheimer’s disease and eight control brains by both single-nucleus assay for transposase-accessible chromatin sequencing (snATAC-Seq) and RNA ...
COMMENT In this manuscript, “An atlas of cortical circular RNA expression demonstrates clinical and pathological associations with Alzheimer disease,” Dube et al. evaluated parietal RNA-Seq data from 13 control and 83 AD samples from Washington University and an ...
COMMENT In 2017, using a whole-exome microarray and genotype imputation, a large three-stage case-control study of 85,133 participants identified an Alzheimer’s Disease (AD) protective coding variant in phospholipase C γ2 (PLCG2; Pro522Arg, rs72824905), a risk ...
