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Mark Cookson on Mitochondrial Jetsam Spurs Neurodegeneration

COMMENT The work from Joshi et al. provides an interesting mechanistic hypothesis to explain how multiple cell types may contribute to several different neurodegenerative diseases. That non-neuronal cells contribute to neuronal cell loss probably has been best ...

Mark Cookson on Parkinson Pathways Branch Out in Flies and Mice

COMMENT The paper by Whitworth and colleagues adds to the work of Plun-Favreau suggesting that there is a relationship between the PINK1/parkin pathway and HtrA2 (aka Omi). Some of the data are very interesting, such as Fgure 4 which shows a change in processing ...

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