Christel Claes, Mathew Blurton-Jones on Janus-Faced PLCγ2? Alzheimer’s Risk Protein Toggles TREM2 and TLR Pathways
COMMENT This exciting new study by Andreone et al. examines the importance of PLCy2 activity downstream of TREM2 signaling for survival, myelin phagocytosis, lipid metabolism, and processing of neuronal debris by human microglia. This work also provides an ...