3 RESULTS
COMMENT This is an impressive proteomic study providing a large list of tau post PTMs identified in different brain extracts including AD brain aggregates containing insoluble tau. The authors performed a semi-quantitative analysis measuring the frequency of ...
COMMENT Suárez-Calvet et al. report the promising performance of novel p-tau assays in cerebrospinal fluid to detect early changes of tau phosphorylation due to amyloid pathology. They monitored a new combination of antibodies capturing different lengths (N-ter ...
COMMENT There is an entire field of exploration to understand the nature of pathological tau species in AD amongst monomeric, oligomeric, and fibrillary and modified tau species. The study by Dujardin et al. provides new insight to posit that seed-competent tau ...
