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Surajit Sarkar on Jumping Genes Rampant in Tau Flies

COMMENT We have previously reported heterochromatin decondensation and global transcriptional upregulation, affecting both protein coding and non-oding genes, in Drosophila tauopathy models. Moreover, we believe that tau-induced heterochromatin decondensation is ...

Axel Montagne on VCAM1: Gateway to the Aging Brain?

COMMENT The concept of “VCAM-1 opening the door to aging” is very interesting and fascinating. Aging has been associated with a low‐grade inflammatory status of the immune system, commonly called “inflammaging,” a contraction of inflammation and aging (Franceschi ...

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