PAPER El Hajjar L, Bridot C, Nguyen M, Cantrelle FX, Landrieu I, Smet-Nocca C
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PAPER Ayoub CA, Moore KI, Kuret J
Quantification of Methylation and Phosphorylation Stoichiometry.
Methods Mol Biol. 2024;2754:221-235. PubMed: 38512670PAPER Zhao Y, Mikes A, Tóth G, Aigbirhio F
Detection of Small-Molecule Interactions with Fibrillar Tau Protein Aggregates Using Microscale Thermophoresis.
Methods Mol Biol. 2024;2754:205-217. PubMed: 38512669PAPER Lin Y
Preparation of Tau Condensates by Liquid-Liquid Phase Separation to Study Tau Amyloid Aggregation.
Methods Mol Biol. 2024;2754:185-192. PubMed: 38512667PAPER Sengupta U, Kayed R
Tau Oligomers as Pathogenic Seeds: Preparation, Characterization, and Propagation In Vitro and In Vivo.
Methods Mol Biol. 2024;2754:147-183. PubMed: 38512666PAPER Horsley D, Rickard JE, Vorley T, Leeper MF, Wischik CM, Harrington CR
Assays for the Screening and Characterization of Tau Aggregation Inhibitors.
Methods Mol Biol. 2024;2754:93-104. PubMed: 38512662PAPER Barbhuiya TK, Jayarathna DK, Gilmour R, Smet-Nocca C, Gandhi NS
Characterization of Posttranslationally Modified PHF-1 Tau Peptides Using Gaussian Accelerated Molecular Dynamics Simulation.
Methods Mol Biol. 2024;2754:3-31. PubMed: 38512658PAPER Słowikowski B, Owecki W, Jeske J, Jezierski M, Draguła M, Goutor U, Jagodziński PP, Kozubski W, Dorszewska J
Epigenetics and the neurodegenerative process.
Epigenomics. 2024 Apr;16(7):473-491. Epub 2024 Mar 21 PubMed: 38511224PAPER Wang Y, Sarnowski C, Lin H, Pitsillides AN, Heard-Costa NL, Choi SH, Wang D, Bis JC, Blue EE, Alzheimer's Disease Neuroimaging Initiative (ADNI), Boerwinkle E, De Jager PL, Fornage M, Wijsman EM, Seshadri S, Dupuis J, Peloso GM, DeStefano AL, Alzheimer's Disease Sequencing Project (ADSP)
Key variants via the Alzheimer's Disease Sequencing Project whole genome sequence data.
Alzheimers Dement. 2024 Mar 21; PubMed: 38511601Leonardo Tejo Gunawan
Hanyang UniversitySeoul, Korea, Republic of
Phillip Janowicz on Fast Plaque Clearance with Little ARIA? So Teases Trontinemab at AD/PD 2024
COMMENT Firstly, I think these results are fantastic and show the possibilities of BBB-crossing immunotherapy. The big question I would have thought is, have the patients been cured? Moreover, or alternatively, if the patients had been treated in their 20s, 30s,
TREM1 Muddles Myeloid Cell Metabolism and Memory in Old Mice
RESEARCH NEWS 2024-03-21 Research News The macrophage and microglial receptor TREM1 whips up inflammation. In its tizzy, the receptor also perturbs myeloid cell metabolism and hastens cognitive decline in older wild-type mice and in two models of amyloidosis, according to scienti
Michal Schwartz on TREM1 Muddles Myeloid Cell Metabolism and Memory in Old Mice
COMMENT The paper by Wilson et al. is extremely timely and important. It attributes a key role to myeloid cells in coping with aging in general, and age-related neurodegenerative diseases in particular, with an emphasis on Alzheimer’s disease, focusing on trigger
Elizabeth Bradshaw, Kirstin Tamucci on TREM1 Muddles Myeloid Cell Metabolism and Memory in Old Mice
COMMENT This paper highlights, and raises questions about, potential crosstalk between the peripheral immune system and central nervous system microglia and how this communication could be a powerful modulator of neurodegeneration. While the authors found very sm
PAPER Zhang C, Kan X, Zhang B, Ni H, Shao J
The role of triggering receptor expressed on myeloid cells-1 (TREM-1) in central nervous system diseases.
Mol Brain. 2022 Oct 22;15(1):84. PubMed: 36273145Current Filters
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