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LRRK2 R1441C KI Mouse

RESEARCH MODELS Overview This knock-in (KI) mouse model was generated by introducing a R1441C missense mutation into the GTPase domain at exon 31 of the mouse Lrrk2 (leucine-rich repeat kinase 2) gene (Tong et al., 2009). As such, this mutation is expressed through the c

‛iNET’ Cultures Expose NPTX2 as TDP-43 Henchman

RESEARCH NEWS 2024-02-23 Research News The pathological accumulation of TDP-43 that underlies many cases of FTD, ALS, and LATE-NC has been notoriously difficult to recapitulate in mice or cultured human cells. In a paper published February 14 in Nature, scientists led by Magdalin

Human Neuroscience Faculty- Open Rank

JOB 2024-02-23 Employer University of Chicago Principal Investigator Joel Voss Contact To be considered, those interested must apply through The University of Chicago‚ Academic Recruitment job board, which uses Interfolio to accept applications:  http://apply.interfolio

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