PAPER Mahaman YA, Huang F, Salissou MT, Yacouba MB, Wang JZ, Liu R, Zhang B, Li HL, Zhu F, Wang X

Ferulic Acid Improves Synaptic Plasticity and Cognitive Impairments by Alleviating the PP2B/DARPP-32/PP1 Axis-Mediated STEP Increase and Aβ Burden in Alzheimer's Disease.

Neurotherapeutics. 2023 Jul;20(4):1081-1108. Epub 2023 Apr 20 PubMed: 37079191

PAPER Hannaway N, Zarkali A, Leyland LA, Bremner F, Nicholas JM, Wagner SK, Roig M, Keane PA, Toosy A, Chataway J, Weil RS

Visual dysfunction is a better predictor than retinal thickness for dementia in Parkinson's disease.

J Neurol Neurosurg Psychiatry. 2023 Sep;94(9):742-750. Epub 2023 Apr 20 PubMed: 37080759

PAPER Imbimbo BP, Watling M, Imbimbo C, Nisticò R

Plasma ATN(I) classification and precision pharmacology in Alzheimer's disease.

Alzheimers Dement. 2023 Oct;19(10):4729-4734. Epub 2023 Apr 20 PubMed: 37079778

D L Chris Diehl

Ryan Bevan

Zaina Rehan

Houston, United States

TREM2 Protects the Brain From Herpes. The Virus Fights Back.

CONFERENCE COVERAGE 2023-04-20 Conference Coverage Retroviruses lurking in the human genome aren’t the only potential troublemakers in neurodegenerative diseases (see Part 5  of this series). Herpes simplex virus type 1 (HSV-1) integrates into the genome of trigeminal ganglia nerves, c

PAPER Liu L, Thorsteinsson K, Jayaweera SW, Avinens D, Bano F, Conca DV, Lovheim H, Olofsson A, Bally M

Recruitment of apolipoprotein E facilitates Herpes simplex virus 1 release

bioRxiv2023.02.10.526562

PAPER Kriesel JD, Jones BB, Matsunami N, Patel MK, St Pierre CA, Kurt-Jones EA, Finberg RW, Leppert M, Hobbs MR

C21orf91 genotypes correlate with herpes simplex labialis (cold sore) frequency: description of a cold sore susceptibility gene.

J Infect Dis. 2011 Dec 1;204(11):1654-62. PubMed: 22039568

PAPER Fruhwurth S, Reinert L, Oberg C, Sakr M, Henricsson M, Zetterberg H, Paludan S

TREM2 is downregulated by HSV1 in microglia and involved in antiviral defense in the brain

bioRxiv2023.03.16.532882

Aleksei Gudkov

Kazakhstan

Marion Trnka

Wien, Austria

Leo Miyakoshi

France

PAPER Shadrina MI, Slominsky PA

Genetic Architecture of Parkinson's Disease.

Biochemistry (Mosc). 2023 Mar;88(3):417-433. PubMed: 37076287

PAPER Rinaldi D, Galli S, Fanciulli A, Pontieri FE

Levodopa/carbidopa intestinal gel via percutaneous endoscopic transgastric jejunostomy in advanced Parkinson's disease: hitting two birds with one stone?

Parkinsonism Relat Disord. 2023 Jul;112:105394. Epub 2023 Apr 10 PubMed: 37076400