PAPER Mishra S, Knupp A, Kinoshita C, Martinez R, Theofilas P, Young JE

Pharmacologic Stabilization of Retromer Rescues Endosomal Pathology Induced by Defects in the Alzheimer's gene SORL1

bioRxiv2022.07.31.502217

Multiomic Analysis Shows Lysosomes Need Retromer to Stay Healthy

RESEARCH NEWS 2023-06-09 Research News The retromer complex controls protein sorting, transport, and disposal via the endolysosome system. It goes awry in neurodegenerative diseases, but how so remains unclear. Metabolism breaks down in cells lacking retromer, according to a mult

AAIC Advancements: Toward Health Equity in ADRD

CONFERENCE 2023-10-30 00:00:00-2023-10-31 00:00:00 San Antonio, Texas and Online 30 &#x2013 31 October 2023 View Conference Website 0

Ian Shiozaki

SENDCon (Southeastern Neurodegenerative Disease Conference)

CONFERENCE 2023-10-10 00:00:00-2023-10-12 00:00:00 Atlanta, Georgia and Online 10 &#x2013 12 October 2023 View Conference Website 0

Annual Congress of the European Academy of Neurology- 10th

CONFERENCE 2024-06-29 00:00:00-2024-07-02 00:00:00 Helsinki, Finland 29 June &#x2013 02 July 2024 View Conference Website 0

Trishawna Watkins

Boston

PAPER Ostrowski M, Carmo NB, Krumeich S, Fanget I, Raposo G, Savina A, Moita CF, Schauer K, Hume AN, Freitas RP, Goud B, Benaroch P, Hacohen N, Fukuda M, Desnos C, Seabra MC, Darchen F, Amigorena S, Moita LF, Thery C

Rab27a and Rab27b control different steps of the exosome secretion pathway.

Nat Cell Biol. 2010 Jan;12(1):19-30; sup pp 1-13. Epub 2009 Dec 6 PubMed: 19966785

Postdoctoral Scientist- Neurobiology

JOB 2023-06-09 Employer MRC Laboratory of Molecular Biology Principal Investigator Benjamin Ryskeldi-Falcon Contact recruit@mrc-lmb.cam.ac.uk Description Postdoctoral Scientist / Career Development Fellow Salary £35,143 per annum The MRC Laboratory of Molecular Biology

PAPER Vera Quesada CL, Rao SB, Torp R, Eide PK

Immunohistochemical visualization of lymphatic vessels in human dura mater: methodological perspectives.

Fluids Barriers CNS. 2023 Mar 28;20(1):23. PubMed: 36978127

Sigrid Veasey on A Failing Sleep Neuropeptide Hypes Up Hippocampus

COMMENT The authors are to be congratulated on their overall approach to define mechanisms underlying early abnormalities in Alzheimer's disease by using an amyloid precursor protein (APP) mutant knock-in model and then defining alterations that temporally c

Philip Hasel on A Failing Sleep Neuropeptide Hypes Up Hippocampus

COMMENT This is another beautiful example of how sequencing-based spatial transcriptomics, despite its relatively low resolution, can be used to generate, or test, hypotheses. Here, the platform was used to identify differentially expressed genes in specific anat

A Failing Sleep Neuropeptide Hypes Up Hippocampus

RESEARCH NEWS 2023-06-09 Research News As amyloid plaques accumulate in the brain, excitotoxic synaptic activity revs up in the hippocampus. In the June Nature Neuroscience, researchers led by Bart De Strooper and Joris de Wit at KU Leuven, Belgium, identified melanin-concentrati

May Simon

Sean Stanton

K2 Medical Research
Winter Park, United States