6120 RESULTS
Sort By:
RESEARCH NEWS 2003-11-26 Research News The potential of RNA interference is exciting, offering the possibility of shutting down expression of specific proteins—perhaps in specific cells—for both investigative and therapeutic purposes (see ARF live discussion on this subject). But
RESEARCH NEWS 2003-11-26 Research News Antibodies have proven to be extremely versatile tools for detecting proteins both in vitro and in vivo, but they need to be coupled to an additional label, such as an enzyme, radioisotope, or fluorophore. Now enter the "fluorobody,&quo
CONFERENCE COVERAGE 2003-11-25 Conference Coverage Are you sometimes tempted to view APP and presenilin merely as raw material and machine for Aβ production, respectively? If so, think again, because that narrow spotlight is opening up to a broader understanding of how these two protei
CONFERENCE COVERAGE 2003-11-21 Conference Coverage At the 33rd Annual Meeting of the Society for Neuroscience held last week in New Orleans, at least two dozen presentations dealt with current efforts to develop a vaccine for Alzheimer’s disease. This bold approach suffered a setback l
CONFERENCE COVERAGE 2003-11-21 Conference Coverage The role of inflammation in Alzheimer’s disease—beyond serious dispute, yet still enigmatic—gained much attention at the 33rd Annual Meeting of the Society for Neuroscience, held last week in New Orleans. While immunotherapy labs are r
RESEARCH NEWS 2003-11-21 Research News Dopaminergic, serotonergic, and glutamatergic: three CNS neurotransmitter pathways that are distinct. Or are they? A paper in this week's Science reveals that all three pathways eventually lead to one protein, the dopamine- and cAMP-reg
RESEARCH NEWS 2003-11-19 Research News In this month's Aging Cell, researchers show that the herpes simplex virus (HSV), traveling away from the neuronal cell body along axons, is associated with the amyloid precursor protein (APP). This finding offers some new insights into
RESEARCH NEWS 2003-11-14 Research News After years as a potential but peripheral suspect in the pathogenesis of Alzheimer's disease, copper (Cu) is lobbying for a new designation—potential therapy! Two studies in the November 17 PNAS Early Edition suggest that copper can inc
RESEARCH NEWS 2003-11-13 Research News Some people are genetically predisposed to specific autoimmune diseases such as rheumatoid arthritis, though for the most part, the reason for their susceptibility is unclear. Now, in this month's Nature Genetics, two papers reveal that
RESEARCH NEWS 2003-11-10 Research News More than 50 years ago, U.S. Navy physicians stationed on Guam found a shocking rate of amyotrophic lateral sclerosis, or ALS—about 50 to 100 times higher than expected. Now, a new paper in the Nov. 11 Proceedings of the National Academy of
RESEARCH NEWS 2003-11-10 Research News The table of evidence regarding inflammatory and even autoimmune processes in Alzheimer's continues to accumulate in a piecemeal fashion, awaiting theoretical frameworks and experimental breakthroughs to give it direction and a greater
RESEARCH NEWS 2003-11-06 Research News According to the six degrees of separation theory, nobody is more than six personal contacts away from anyone else on the planet. In the human world, it may not always work like that, but how about the protein world, which is considerably sm
RESEARCH NEWS 2003-11-06 Research News Gerard Drewes and colleagues at Cellzome, Heidelberg, Germany, and the University of Kansas at Lawrence, report in the November 1 Journal of Biological Chemistry online the characterization of a tau kinase called MARK 4. Tau, of course, is a
RESEARCH NEWS 2003-11-05 Research News Though neurons are the obvious stars of the nervous system, glia are getting more attention lately as research uncovers their importance in keeping the CNS disease-free (see ARF related news story). Now, Gabriel Corfas and colleagues at Chil
RESEARCH NEWS 2003-11-04 Research News Most AD investigators would much rather ponder the meaning of a smudge on a 2-D gel than that of a cryptic court decision, but, like it or not, intellectual property law reaches into research labs. On 20 October, a group of technology transf
