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CONFERENCE COVERAGE 2015-08-07 Conference Coverage The Alzheimer’s Association International Conference, held July 18 to 23 in Washington, D.C., showcased a growing interest in early brain changes beyond the established markers of amyloid, tau, and brain volume that anchor the diagrams
CONFERENCE COVERAGE 2015-08-10 Conference Coverage “Failures, repeated failures, are finger posts on the road to achievement. One fails forward toward success.” C.S. Lewis. Flashed onto the projection screen by Roche’s Robert Lasser, the Irish novelist’s quote symbolized the “chin-up!”
RESEARCH NEWS 2015-08-12 Research News If you can’t beat 'em, keep them joined? That is the basis of a new therapy that stops the spread of prions in its tracks. As described August 5 in Science Translational Medicine, researchers have developed polythiophene compounds that
CONFERENCE COVERAGE 2015-08-13 Conference Coverage Part 1 of two. Could Alzheimer’s disease be tempered by just by working up a sweat? Speakers at the Alzheimer's Association International Conference 2015, held July 18-23 in Washington, D.C., presented new evidence that regular ae
CONFERENCE COVERAGE 2015-08-13 Conference Coverage Part 2 of two. Evidence for the cognitive benefits of exercise keeps growing, but researchers are still not sure how it helps the brain. At the Alzheimer's Association International Conference 2015, held July 18-23 in Washington,
CONFERENCE COVERAGE 2015-08-19 Conference Coverage As amyloid fibrils hog Aβ in the brain, less ends up in the cerebrospinal fluid. Myriad studies suggest that this dearth correlates with a positive amyloid PET scan. However, the use of CSF Aβ as diagnostic tool has been stymied by lab
CONFERENCE COVERAGE 2015-08-20 Conference Coverage It’s clear by now that in dementia, a disease mostly of old age, trouble starts decades earlier—but how early? Well—how about in the womb? Data presented at the Alzheimer's Association International Conference, 2015, held July 18-
RESEARCH NEWS 2015-08-20 Research News Like factory workers in a processing line, β- and γ-secretase make successive snips in amyloid precursor protein (APP), releasing Aβ peptides. Now, a study reports that this enzymatic duo also coordinates axon growth—a key factor in neural d
RESEARCH NEWS 2015-08-21 Research News It can be hard to tell one parkinsonian disorder from another based on clinical tests alone. Though their underlying pathologies differ, these degenerative brain disorders all affect movement, and at early stages they resemble one another. P
CONFERENCE COVERAGE 2015-08-21 Conference Coverage Last month in Washington, D.C., while U.S. political pundits eyed presidential hopefuls, researchers at the Alzheimer’s Association International Conference (AAIC) were scrutinizing neurogranin, a synaptic protein found in cerebrospina
CONFERENCE COVERAGE 2015-08-26 Conference Coverage Part 1 of two. With the growing use of biomarkers, researchers can now identify cognitively normal people who are at elevated risk for Alzheimer’s disease. This has enabled secondary prevention studies such as the Anti-Amyloid Treatmen
CONFERENCE COVERAGE 2015-08-26 Conference Coverage Part 2 of two. With Alzheimer’s secondary prevention trials now underway, the question of how best to tell people about their AD risk has arrived. The ongoing Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) trial uses a
CONFERENCE COVERAGE 2015-08-27 Conference Coverage Amyloid scans have allowed researchers to follow Alzheimer’s pathology as it develops in the human brain, but they are still working out whether and how this technology will help patients. At the Alzheimer’s Association International C
RESEARCH NEWS 2015-08-27 Research News A Global View: The World Alzheimer Report 2015 updates statistics on the international plight of dementia. [World Alzheimer Report 2015, ADI.] Alzheimer’s Disease International yesterday released its World Alzheimer Report 2015: The Global I
RESEARCH NEWS 2015-09-03 Research News The hormone estrogen has a long and fitful history in Alzheimer’s research, and at the recent Alzheimer’s Association International Conference, scientists grappled anew with its possible impact on amyloid-β deposition, brain structure, and r
