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RESEARCH NEWS 2015-01-09 Research News Some cases of Alzheimer’s disease progress quickly, mimicking prion-based Creutzfeldt-Jakob disease (CJD). Many people with this form of Alzheimer’s are misdiagnosed, because clinicians have no reliable way to distinguish between the two dis
RESEARCH NEWS 2015-01-09 Research News For a neuroprosthetic device to deliver lasting treatment to an injured nervous system, it has to integrate seamlessly with the surrounding tissue and avoid rejection by the immune system. Researchers led by Grégoire Courtine and Stéphanie L
RESEARCH NEWS 2015-01-09 Research News When amyotrophic lateral sclerosis attacks motor neurons, certain types resist while others surrender. If scientists can figure out why some neurons hang tough, they may be able to offer that same protection to those that succumb. Smita Saxe
RESEARCH NEWS 2015-01-13 Research News For some, it starts with stealing candy. For others, it’s a reckless car crash, or a sudden penchant to urinate in public. The type of incident varies, but according to a study published January 5 in JAMA Neurology, more than a third of peop
RESEARCH NEWS 2015-01-14 Research News The European Union Committee for Medicinal Products for Human Use (CHMP) has recommended that the European Commission approve the drug Xadago for Parkinson’s disease (PD) as an add-on treatment to levodopa (see company press release). Going
RESEARCH NEWS 2015-01-15 Research News In trouble with the FDA, the personal genomics company 23andMe stopped sharing specific genotype information with its customers back in 2013, but by then it had already amassed a fortune in genetic gold. Now that treasure trove of DNA is pay
RESEARCH NEWS 2015-01-16 Research News Studies of familial and sporadic Alzheimer’s disease paint a remarkably consistent picture of how biomarkers change in preclinical stages. Now, new cross-sectional biomarker data from the Alzheimer’s Prevention Initiative’s Colombian kindred
RESEARCH NEWS 2015-01-16 Research News A computer model does a pretty good job of predicting where in the brain Alzheimer’s pathology will strike next, according to a paper in the January 20 Cell Reports. Ashish Raj and colleagues at Weill Cornell Medical College in New York, who
RESEARCH NEWS 2015-01-21 Research News Researchers have identified some of the earliest known defects in mouse models of amyotrophic lateral sclerosis, according to two papers in the January 14 Journal of Neuroscience. Signs of something amiss emerge within just a few weeks of bi
RESEARCH NEWS 2015-01-21 Research News Could neuropsychiatric symptoms herald Alzheimer's disease? Sometimes, according to a paper in the January 14 Neurology online. Catherine Roe and colleagues at the Washington University School of Medicine in St. Louis found that while p
RESEARCH NEWS 2015-01-23 Research News Early on in amyotrophic lateral sclerosis motor, neurons fire like machine guns, but then they run out of ammo and go silent, according to a paper in the January 12 Nature Communications. Researchers from the University of St. Andrews in Sco
RESEARCH NEWS 2015-01-23 Research News One strategy scientists are trying to slow the progression of Alzheimer’s is inhibiting the BACE1 enzyme that cleaves the amyloid precursor protein (APP). However, since BACE1 cuts a range of other substrates, side effects are a concern. One
RESEARCH NEWS 2015-01-25 Research News Amyloid plaques and tau tangles both characterize Alzheimer’s, but how does each drive the disease? A new study in the February 3 Cell Reports aims to disentangle their relative contributions to AD pathology. Researchers led by Frances Edwar
RESEARCH NEWS 2015-01-27 Research News Could an astrocyte receptor explain some of the memory deficits of Alzheimer’s disease? So suggest scientists in the January 26 Nature Neuroscience. Researchers led by Lennart Mucke of Gladstone Institute of Neurological Disease, San Francis
COMMUNITY NEWS 2015-01-29 Community News An easy word escapes her mid-lecture. Then she loses her way jogging familiar campus roads. These and other unsettling memory lapses prompt 50-year-old Alice Howland, a vivacious linguistics professor at the height of her career, to consult
