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PET Tracer PI-2620 Detects 4R Tau Deposits

RESEARCH NEWS 2020-07-10 Research News Tau tracers have invigorated Alzheimer’s research, but they initially proved disappointing for other tauopathies. That is now changing, with at least two tracers, PI-2620 and APN-1607, that appear to bind specifically to the 4R tau deposits

In APP Knock-In Mice, Spatial Mapping Circuitry Crumbles

RESEARCH NEWS 2020-07-24 Research News People with Alzheimer’s get lost in once-familiar places, often quite early in their disease. A study published July 13 in Neuron helps explain why. Researchers led by Kei Igarashi at the University of California, Irvine, reported that in AP

Doubling Down on Sequencing Serves up More Alzheimer’s Genes

CONFERENCE COVERAGE 2020-07-31 Conference Coverage The list of rare and common genetic variants that sway a person’s risk of Alzheimer’s disease just got substantially longer, as researchers expanded both the breadth and depth of genomic studies aimed at uncovering the etiology of the

IDEAS Finds Small Drop in Hospitalizations, Missing Goal

CONFERENCE COVERAGE 2020-08-01 Conference Coverage Numerous studies have now found that amyloid PET scans can alter a person’s diagnosis and disease management—but do they reduce overall medical costs? According to data from the final phase of the IDEAS study, presented at the virtual

Lancet Commission’s Dementia Hit List Adds Alcohol, Pollution, TBI

CONFERENCE COVERAGE 2020-08-04 Conference Coverage At this year’s virtual Alzheimer’s Association International Conference, researchers presented an update to “Dementia prevention, intervention, and care,” the 2017 report commissioned by The Lancet. Published July 30, the new report id

Heart Health Is Brain Health, and It Starts in Your 20s

CONFERENCE COVERAGE 2020-08-07 Conference Coverage Having established that poor cardiovascular health in midlife increases the risk of cognitive decline and dementia as a person ages, scientists are now pushing to see if the same relationship might hold true even earlier in life. Indee

FDA Accepts Aducanumab Application for Priority Review

RESEARCH NEWS 2020-08-08 Research News The fate of aducanumab now rests in the hands of regulators at the U.S. Food and Drug Administration (FDA). Biogen of Cambridge, Massachusetts, and Eisai Co. Ltd., Tokyo, announced on August 7 that the agency had accepted its Biologics Licen

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