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Parkinson's Therapies Seek to Stem Progression

CONFERENCE COVERAGE 2020-04-22 Conference Coverage At the second biannual Advances in Alzheimer’s and Parkinson’s Therapies Focus Meeting (AAT-AD/PD), held virtually April 2 to 5, companies offered some news on investigational Parkinson’s therapies in Phase 1. One approach is targeted ...

The Air We Breathe—How Might Pollution Hurt the Brain?

RESEARCH NEWS 2020-05-23 Research News Part 2 of 2 For decades, studies of pulmonary and vascular systems dominated the air-pollution-research landscape. Researchers paid scant attention to the brain, which they considered safely ensconced behind the blood-brain barrier. But the ...

Air Pollution and Dementia—Through Hazy Data, Links Emerge

RESEARCH NEWS 2020-05-22 Research News Part 1 of 2 As coronavirus lockdowns have led to noticeably clearer skies above many metropolitan areas, people are beginning to wonder anew about the effects of air pollution. Traffic and industrial exhaust have long been linked to ...

Shiny SEQUIN: New Technique Counts Synapses Over Large Brain Volumes

RESEARCH NEWS 2020-06-01 Research News Synapses are central in Alzheimer’s disease, but they are hard to study. The microscopic techniques that offer a glimpse at these tiny structures require expensive equipment and laborious ultra-sectioning of brain tissue, and cover only very ...

Primary Tauopathies Get New PET Ligands

CONFERENCE COVERAGE 2020-03-06 Conference Coverage Scientists studying the non-Alzheimer’s disease tauopathies have struggled to find tracers that will bind the particular forms of tau that predominate in those diseases. At Tau2020, held February 12–13 in Washington, D.C., Gil ...

New Assay, New Cohorts—Plasma p-Tau181 Looks Even Better

CONFERENCE COVERAGE 2020-04-03 Conference Coverage The conference may be virtual, but the data is real. At the online AAT-ADPD 2020, researchers presented their talks and posters in much that same way as they would have in person—albeit without the open question-and-answer time. Up ...

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