72 RESULTS
COMMUNITY NEWS 2019-06-25 Community News Today the co-founders of the preprint server bioRχiv, together with The BMJ in London and Yale University in New Haven, Connecticut, launch a sister repository for research papers in the medical sciences. Called medRχiv, this free, nonprofi
RESEARCH NEWS 2019-06-26 Research News Microglia, the ever-changing resident immune cells of the central nervous system, have come under intense scrutiny for their role in Alzheimer’s disease and other neuroinflammatory conditions. Tracking these famously elusive cells just got e
RESEARCH NEWS 2019-06-28 Research News Microglia do much of the heavy lifting when it comes to removing Aβ, but how do they do it? Researchers led by Douglas Green, St. Jude Children’s Research Hospital, Memphis, Tennessee, have identified an endocytic recycling process by which
CONFERENCE COVERAGE 2019-07-02 Conference Coverage That microglia play a central role in neurodegenerative disease has become a premise; it’s no longer a question. The questions are all about the how. This was abundantly clear at joint symposia held June 16–21 in Keystone, Colorado. At
CONFERENCE COVERAGE 2019-07-02 Conference Coverage Some microglia are from Mars; others from Venus. Well, no. But in some scenarios, to which sex a microglial cell belongs appears to hold some sway over how it responds. Consider tau. At a joint Keystone symposia—Neurodegenerative Disea
CONFERENCE COVERAGE 2019-07-05 Conference Coverage Astrocytes are devoted nurturers of neurons—facilitating synaptic transmission, maintaining the blood-brain barrier, and repairing injuries are but a few of their ministrations. As if that weren’t enough, scientists described an instan
RESEARCH NEWS 2019-07-06 Research News Adult mammalian brains eke out limited numbers of new neurons in select regions, but over time, even that production dwindles. Why is unclear. New evidence from the lab of Anne Brunet, Stanford University, California, suggests invading immun
RESEARCH NEWS 2019-07-10 Research News The drug edonerpic maleate failed to slow cognitive decline in Alzheimer’s patients, according to a paper published online July 8 in JAMA Neurology. Scientists led by Lon Schneider, University of Southern California, Los Angeles, reported th
RESEARCH NEWS 2019-07-11 Research News From their perch on the microglial surface, CD33 and TREM2 exact opposing forces on microglial functions, including phagocytosis and inflammatory responses. Now, in a study published in Neuron on July 10, researchers led by Rudolph Tanzi at
CONFERENCE COVERAGE 2019-07-12 Conference Coverage The hypothesis that Parkinson’s disease could arise within the belly, not the brain, now gains support with a new mouse model. Valina Dawson of Johns Hopkins University, Baltimore, reported at a joint symposium held June 16-21 in Keyst
CONFERENCE COVERAGE 2019-07-14 Conference Coverage This is Part 2 of a two-part story. At a workshop during the 11th International Conference on HHV-6 and HHV-7, held June 23 to 26, 2019, in Quebec City, Canada, experts on human herpesviruses treated Alzheimer’s researchers to a lesson
CONFERENCE COVERAGE 2019-07-19 Conference Coverage Lewy body dementia, the second-most-common progressive dementia after Alzheimer’s disease, receives relatively little attention and few research dollars, and often goes undiagnosed. Comedian Robin Williams, perhaps the most famous pers
CONFERENCE COVERAGE 2019-07-20 Conference Coverage Research into dementia with Lewy bodies has lagged behind that for Alzheimer’s and Parkinson’s diseases, in part because DLB is difficult to identify, and less common. Many DLB trials fold because enrollment goals cannot be met. To ena
CONFERENCE COVERAGE 2019-07-21 Conference Coverage For neurodegenerative disease, the mantra is “go early,” based on the theory that intervention at prodromal stages may be most effective. Early detection could also help patients and families plan for the future, and avoid drugs contra
CONFERENCE COVERAGE 2019-07-25 Conference Coverage Physical activity not only benefits the heart and the body, it may also shield the brain from the damaging effects of Aβ. That’s according to findings presented at the Alzheimer’s Association International Conference, held July 14–18 i
