72 RESULTS
RESEARCH NEWS 2019-09-06 Research News Two papers in the September 2 Nature Cell Biology present complementary evidence that tau condenses into a patchwork of rafts that coat microtubules. These patches share some properties with phase-separated liquid droplets of tau that have b
RESEARCH NEWS 2019-09-11 Research News Mitochondria may be the universal powerhouses of eukaryotic cells, but there is more to these organelles than just ATP production. According to a paper in the September 9 Nature Neuroscience, mouse mitochondria express distinct subsets of pr
RESEARCH NEWS 2019-09-13 Research News The humble locus coeruleus, a minute speck of tissue nestled deep in the brain stem, has received relatively scant attention in studies of cognitive decline. Now, data published September 9 in Nature Human Behavior add to a recent spate of f
RESEARCH NEWS 2019-09-14 Research News New research adds to the evidence that ApoE regulates microglial health and activity. Researchers led by Tarja Malm at the University of Eastern Finland, Kuopio, examined how several Alzheimer’s risk factors affect microglia generated from h
RESEARCH NEWS 2019-09-04 Research News Are microglia the masterminds of amyloid plaque formation? In the August 21 Nature Communications, researchers led by Kim Green at the University of California, Irvine, suggest these cells seed amyloid deposits. In a mouse model of amyloidos
RESEARCH NEWS 2019-07-16 Research News Two recent papers detail stumbles and strides for tau models. In the June 6 Nature Communications, scientists led by Michael Koob and Karen Ashe, University of Minnesota, Minneapolis, reported that most of the rampant neurodegeneration seen
RESEARCH NEWS 2019-08-01 Research News As microglia become more central to Alzheimer’s research, researchers are seeking better model systems to study their in vivo behavior. In culture, the cells rapidly alter their gene expression, and mouse microglia respond differently to dis
RESEARCH NEWS 2019-06-24 Research News In today’s JAMA Neurology, researchers led by Oskar Hansson, Lund University, Sweden, report how a fully automated immunoassay for plasma Aβ performed when they put it through its paces. Roche Diagnostic’s Elecsys system predicted Aβ-positiv
RESEARCH NEWS 2019-06-28 Research News Parkinson’s disease inflicts brain damage years before patients begin shaking, slowing down, and feeling stiff. What happens before motor symptoms surface, however, remains murky. In a study in the June 19 Lancet Neurology, researchers led b
RESEARCH NEWS 2019-07-03 Research News In the largest U.S. study to date on androgen-deprivation therapy and dementia, researchers led by Ravishankar Jayadevappa, University of Pennsylvania, Philadelphia, found that among older men with prostate cancer, those who received this tr
COMMUNITY NEWS 2019-07-05 Community News A bitter dispute that pitted the University of California, San Diego, against the University of Southern California and Paul Aisen has been settled. USC will pay UCSD $50 million to compensate for its sudden recruitment of Aisen and other s
CONFERENCE COVERAGE 2019-07-11 Conference Coverage This is Part 1 of a two-part story. In a rare meeting of two worlds, experts on human herpesviruses and Alzheimer’s disease shared the stage at a special workshop at the 11th International Conference on HHV-6 and HHV-7, held June 23 to
RESEARCH NEWS 2019-09-07 Research News Traumatic brain injuries trigger tau pathology and raise the risk of developing dementia later in life. Could tau PET tracers help researchers pick out those on the path to neurodegeneration? Yes, according to a paper in the September 4 Scie
RESEARCH NEWS 2019-09-20 Research News A drug commonly prescribed to keep enlarged prostates in check may hold promise for Parkinson’s disease. According to a study published September 16 in the Journal of Clinical Investigation, terazosin (TZ), an α1-adrenergic receptor antagoni
CONFERENCE COVERAGE 2019-07-19 Conference Coverage Microglia not only gobble up detritus from dead cells, they also have a penchant for chowing down on live ones. At a Keystone joint symposia—Neurodegenerative Diseases: New Insights and Therapeutic Opportunities and Neural Environment
