International Symposium Puts PSP/CBD on the Map

CONFERENCE COVERAGE 2018-11-08 Conference Coverage Progressive supranuclear palsy and corticobasal degeneration are rare, poorly understood tauopathies with a broad array of symptoms and subtypes. What causes them? How to prevent, diagnose, track, and treat them? On October 25 and 26, ...

Off-Balance Endocytosis Lays Groundwork for Disease

CONFERENCE COVERAGE 2019-05-03 Conference Coverage Endocytosis is implicated in Alzheimer’s pathogenesis, because the continuous swallowing up of proteins from the cell surface and packaging them into little organelles brings the amyloid precursor protein (APP) into contact with the ...

Parsing How Alzheimer’s Genetic Risk Works Through Microglia

CONFERENCE COVERAGE 2019-04-23 Conference Coverage Much of the genetic risk of Alzheimer’s disease plays out in microglia. But exactly how do risk variants change these cells? At the 14th International Conference on Alzheimer’s and Parkinson’s Diseases, held March 27–31 in Lisbon, ...

Which Are the Right Tests to Satisfy New FDA Guidance?

CONFERENCE COVERAGE 2018-11-27 Conference Coverage As researchers push toward testing Alzheimer’s drugs at presymptomatic stages, the hurdle before them—how to show efficacy and get a drug approved—looks different than before. In its February 2018 draft guidance for industry, the U.S. ...

Antisense Oligonucleotides: Can They Take on ALS, SMA, Prions?

CONFERENCE COVERAGE 2019-05-22 Conference Coverage At the American Academy of Neurology’s 71st Annual Meeting, held May 4–10 in Philadelphia, researchers showcased their latest data on antisense oligonucleotides (ASOs). These short, synthetic, single-stranded oligodeoxynucleotides bind ...

Herpesvirus: Trigger for Many Brain Pathologies?

CONFERENCE COVERAGE 2019-07-14 Conference Coverage This is Part 2 of a two-part story. At a workshop during the 11th International Conference on HHV-6 and HHV-7, held June 23 to 26, 2019, in Quebec City, Canada, experts on human herpesviruses treated Alzheimer’s researchers to a lesson ...

Can Induced Neurons Identify Early Signs of Neurodegeneration?

CONFERENCE COVERAGE 2019-09-07 Conference Coverage Researchers have linked dozens of genetic loci to late-onset Alzheimer’s disease and found dozens more that cause familial forms of AD and other neurodegenerative diseases. Teasing out how each contributes to pathology has proven a ...

11th ICFTD Meeting in Sydney Sorts Out Clinical Subtypes

CONFERENCE COVERAGE 2018-12-04 Conference Coverage Indigenous Australian people opened the 11th International Conference on Frontotemporal Dementia at the International Convention Center, Sydney, November 11–14. Koomurri performers welcomed more than 600 attendees from 37 countries. ...

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