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RESEARCH NEWS 2015-12-23 Research News Researchers know that repeated blows to the head can precipitate a neurodegenerative tauopathy called chronic traumatic encephalopathy (CTE). Marked by memory loss, movement problems, and changes in mood such as depression and anger, this di
CONFERENCE COVERAGE 2015-12-23 Conference Coverage Dementia with Lewy bodies is a common α-synucleinopathy that blends dementia with parkinsonism and psychiatric illness. When scientists met on December 1-4 in Fort Lauderdale, Florida, for the International Dementia with Lewy Bodies Co
CONFERENCE COVERAGE 2015-12-28 Conference Coverage At the International Dementia With Lewy Body Conference, held December 1-4 in Fort Lauderdale, Florida, scientists suggested that concurrent amyloid pathology in DLB explains some of the overlap between DLB and Alzheimer’s disease (see
CONFERENCE COVERAGE 2015-12-29 Conference Coverage Besides ample new data presentations, the International Dementia with Lewy Body Conference December 1-4 in Fort Lauderdale, Florida, featured a reprise of the field's perennial debate. It is the verbal tug-of-war between movement
RESEARCH NEWS 2015-12-31 Research News With more money for Alzheimer’s research than ever before, 2016 is shaping up to be a promising year. How will the developments of 2015 influence your research decisions? Alzforum reflects on some of this year’s news. Funding December brough
CONFERENCE COVERAGE 2016-01-08 Conference Coverage Edaravone, a medication that scrubs cells of toxic free radicals, may help a subset of people with amyotrophic lateral sclerosis. That was the upshot of a presentation at the International Symposium on ALS/MND, held December 11 to 13 i
RESEARCH NEWS 2016-01-14 Research News A person’s own bone marrow stem cells, souped up to pump out neuroprotective molecules, are a safe investigational treatment for amyotrophic lateral sclerosis, according to a paper in the January 11 JAMA Neurology online. The organizers of t
CONFERENCE COVERAGE 2016-01-15 Conference Coverage The first outward sign of amyotrophic lateral sclerosis (ALS) usually crops up in one spot: a little trouble swallowing, or weakness in one leg or one arm. Then it spreads. Scientists now suspect the underlying pathogenic proteins, suc
COMMUNITY NEWS 2016-01-21 Community News After months of public acrimony over the Alzheimer’s Disease Cooperative Study, the University of California, San Diego, announced on January 14 that Howard Feldman would take over the embattled clinical trials network as part of a broader
RESEARCH NEWS 2016-01-27 Research News Ever since rare variants in the microglial receptor TREM2 were identified as a major risk factor for Alzheimer’s, researchers have been trying to figure out how the protein fits into the pathogenesis of this long, slow disease. Two recent pa
CONFERENCE COVERAGE 2016-01-28 Conference Coverage Since it started in 2007 as a one-day powwow of 150 early aficionados in Boston, the annual Human Amyloid Imaging meeting has become a fixture for anyone using imaging technology to study dementia-related pathology in the brain. At the
COMMUNITY NEWS 2016-01-29 Community News This month saw one of the worst drug trial debacles in memory, when a healthy volunteer participating in a Phase 1 study in France died within days of receiving an experimental drug for anxiety and chronic pain. Four other volunteers who to
CONFERENCE COVERAGE 2016-02-02 Conference Coverage PET imaging transformed Alzheimer’s research when it enabled scientists to track the spread of Aβ pathology in living people. It revealed that amyloid plaques appear decades before symptoms of Alzheimer’s disease emerge. But what about
RESEARCH NEWS 2016-02-05 Research News A single severe head injury—the kind that comes from a car accident or a hard fall—raises the risk for dementia later in life (Aug 2012 news on Alzrisk entry). What causes neurodegeneration in these situations? Is the end result Alzheimer’s
RESEARCH NEWS 2016-02-05 Research News The emergence of PET ligands for tau has the potential to revolutionize the study of the whole gamut of tauopathies. Researchers are tracking how neurofibrillary tangles appear and spread in real time, yielding invaluable insight into the pa
