RESEARCH NEWS 2003-05-09 Research News On May 4-5, Harvard Medical School briefed reporters on new directions in biomedical research. The meeting featured diverse presentations ranging from basic research on RNA splicing and clinical trials of proteasome inhibitors to the evoluti
CONFERENCE COVERAGE 2003-05-06 Conference Coverage Successful radiotracers for positron emission tomography (PET) diagnosis of AD are a mere year or two away, according to leading researchers who met on May 1-2 in New York. The real challenge now will be in convincing the Food and Drug
RESEARCH NEWS 2003-05-02 Research News In today's Science, researchers report that mutations in the protein dynein-the motor that drives the transport of large molecules from the synaptic terminal back to the neuron’s cell body-can lead to forms of neurodegeneration reminisc
RESEARCH NEWS 2003-05-02 Research News Neuronal progenitors are faced with many forks on the road to becoming one of more than 1,000 different neurons found in the human central nervous system. Tracking exactly what pathways progenitors take to become a specific type of neuron ha
RESEARCH NEWS 2003-05-01 Research News Counterintuitive as it may seem, in tomorrow's Science researchers report that the inhibitory neurotransmitter ã-aminobutyric acid (GABA) can temporarily restore age-related losses of visual acuity in monkeys. Audie Leventhal, Universit
RESEARCH NEWS 2003-04-27 Research News In this week's Journal of the American Medical Association, researchers report a correlation between Alzheimer's disease (AD) and the appearance in the cerebrospinal fluid (CSF) of two proteins thought to play major roles in the pr
RESEARCH NEWS 2003-04-27 Research News Several anticholesterol drugs, particularly statins, at standard doses can significantly reduce plasma levels of the brain cholesterol degradation product 24S-hydrocholesterol, according to a report in this week's Archives of Neurology.
RESEARCH NEWS 2003-04-24 Research News There is growing interest in the overlap among Alzheimer's disease, Parkinson's disease, and less common synucleinopathies and tauopathies that can share features of both diseases. Two current papers looking at different levels of
RESEARCH NEWS 2003-04-18 Research News Like good cholesterol and bad cholesterol, the Alzheimer's community has realized that there may also be good Aβ and bad Aβ. What if an antibody was developed to target only the latter? A tall order, yet scientists from the University o
RESEARCH NEWS 2003-04-17 Research News Stem cells injected into the cerebral ventricles-or even injected intravenously-find their way to sites of inflammation in an animal model of multiple sclerosis (MS), according to a report in today’s Nature. Once there, they replace the dama
RESEARCH NEWS 2003-04-16 Research News What happens when the protein machinery that drives the cell division cycle gets activated in non-dividing cells such as neurons? The cells will most likely die. Recent evidence suggests that just this type of scenario plays out in the brain
RESEARCH NEWS 2003-04-14 Research News In this month's Journal of Medical Genetics, a group of Italian researchers propose that there is a link between longevity and a single nucleotide polymorphism (SNP) in the promoter for the antiinflammatory cytokine interleukin-10 (IL-1
CONFERENCE COVERAGE 2003-04-11 Conference Coverage Almost exactly 100 years after Alois Alzheimer saw his first patient who complained about "having lost herself," Christian Haass and Roger Nitsch invited a panel of international opinion leaders to gather in the German Black
CONFERENCE COVERAGE 2003-04-11 Conference Coverage Almost exactly 100 years after Alois Alzheimer saw his first patient who complained about "having lost herself," Christian Haass and Roger Nitsch invited a panel of international opinion leaders to gather in the German Black